Mitochondrial Dysfunction and Chronic Fatigue

Woman in her 30's-40's experiencing chronic fatigue and exhaustion due to mitochondrial dysfunction

You get enough sleep. You eat reasonably well. You don’t have an obvious medical condition. Yet you feel exhausted most of the time, struggling to get through basic daily activities that used to require no effort at all. This kind of persistent, unexplained fatigue affects millions of people, and while the causes can be complex, … Read more

Sirtuins: The Longevity Proteins Activated by NAD+

Healthy aging and longevity through sirtuin activation shown by active older adult exercising outdoors

If you’ve heard anything about anti-aging research in the past two decades, you’ve probably come across the term “sirtuins.” These proteins have been called the guardians of the genome, the longevity genes, and the key to understanding why some organisms live longer than others. But sirtuins aren’t magic, and they don’t work alone. They depend … Read more

What Is NAD+ and Why Does It Decline With Age

Abstract visual representation of cellular energy/NAD+ decline from youth to aging

You might not have heard of NAD+ until recently, but this molecule has been quietly keeping you alive since the day you were born. It’s involved in more than 500 enzymatic reactions in your body, playing a critical role in everything from energy production to DNA repair. The problem is, NAD+ levels don’t stay constant. … Read more

NAD+ and Brain Health: Supporting Cognitive Function as You Age

Revised Alt Text: Woman in her 50s reviewing documents with focus showing cognitive clarity and NAD+ supported brain health

You notice it in small ways at first. Names take longer to recall. You lose your train of thought mid-sentence. Reading the same paragraph twice doesn’t help it stick. By the end of a long workday, your brain feels like it’s running through mud. Most people chalk this up to stress, lack of sleep, or … Read more

Sleep Quality After Drinking: Why You Wake Up Exhausted

Person lying awake in bed at night unable to sleep after drinking alcohol showing disrupted sleep patterns

You had a few drinks, fell asleep easily, and logged a solid seven or eight hours. So why do you feel like you barely slept at all? The exhaustion that follows a night of drinking isn’t just about dehydration or a headache. Alcohol fundamentally disrupts your sleep architecture, the structured pattern of sleep stages your … Read more

Magnesium Depletion from Alcohol: Why Your Body Aches After Drinking

Magnesium-rich foods including leafy greens, nuts, seeds, and avocado for recovery after drinking

You wake up after a night of drinking, and everything hurts. Your head is pounding, your muscles are sore, and even your jaw feels tight. You might chalk it up to “just a hangover,” but there’s a specific reason why alcohol leaves you feeling physically battered: magnesium depletion. Magnesium is one of the most important … Read more

The Science Behind Hangover Headaches

Person experiencing hangover headache holding head in pain with water nearby

The pounding, throbbing headache that arrives the morning after drinking is one of the most recognizable and dreaded hangover symptoms. It can turn even simple tasks like getting out of bed or looking at a screen into painful ordeals. But what actually causes that relentless ache? The answer isn’t as simple as “you’re dehydrated,” though … Read more

Why Hangovers Get Worse With Age

Young man celebrating at night versus older man with headache drinking water the next morning showing age-related hangover differences

Remember your early twenties, when you could drink all night and wake up the next morning ready to go? Maybe you felt a little rough around the edges, but nothing a greasy breakfast and some coffee couldn’t fix. Fast forward a decade or two, and suddenly two glasses of wine leave you feeling like you’ve … Read more

Beyond Thirst: Recognizing When Your Body Needs Immediate Hydration

Health illustration showing the progression from subtle dehydration symptoms to optimal immediate hydration, featuring a professional experiencing cognitive changes and physical signs before thirst appears

You’ve just finished a three-hour presentation to potential clients, fielding questions and maintaining your energy throughout the entire session. As you pack up your materials, you notice a dull headache beginning to form behind your eyes. Your mouth feels slightly sticky, but you wouldn’t necessarily say you’re thirsty. You chalk it up to the stress … Read more